Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their ...
A new understanding of how drugs are taken in by cells could impact the way drugs are administered to patients. In an Aug. 30 study published in Nature that details structural changes of the Transient ...
The interplay between ion channels and T cell immunology has emerged as a pivotal area in both basic and translational research. Ion channels, particularly voltage‐gated potassium channels such as Kv1 ...
A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a new study. The discovery is a ...
Unlike conventional computing hardware, biological computation occurs in wet, salty environments through carefully-controlled chemical and ionic transport between neurons. Their thin cellular ...
They are literally channels for communication: Pore-forming proteins in living cells, termed ion channels, are embedded in the outer membrane of almost all cell types and play a crucial role in the ...
In a surprising new finding, neuroscientists have shown that human neurons have a much lower density of ion channels than expected, compared to the neurons of other mammals. Ion channels produce ...
Cells send electrical impulses throughout the body, but electrophysiologists struggled to tune into these signals until the patch clamp technique was developed. Although biophysicist Bernard Katz from ...
Every hug, every handshake, every dexterous act engages and requires touch perception, and so understanding the molecular basis of touch is important. But to date, scientists had only known about one ...
Ion channels enable passive ion flow towards equilibrium, which is driven by ion concentration differences across the membrane and the membrane potential (the difference electric potential between the ...
The present study has shown that changes in ionic channel currents accompany the phagocytosis of particles by mononuclear phagocytes. The patch-clamp technique in the cell-attached configuration was ...
Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers have ...