When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that ...

Chemotherapy drugs like doxorubicin and etoposide work by snapping a cancer cell’s DNA in two. The breaks are supposed to be ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

The molecular choreography of DNA replication is a finely balanced process ensuring that genetic information is faithfully transmitted during cell division. Replication initiation begins with origin ...

For decades, oncologists have watched a frustrating pattern repeat itself. Tumors fueled by the MYC protein, one of the most ...

Researchers at The University of Texas Medical Branch (UTMB) have identified how a key enzyme called ATR protects DNA from ...

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life. A new study from King ...

Within the nucleus of every cell are long strings of DNA, the code that holds all the information needed to make and control every cell within a living organism. DNA, which stands for deoxyribonucleic ...

Structural biologists at the University of Wisconsin-Madison today published cryo-electron microscopy structures of the complete bacterial DNA replication restart complex — a molecular machine that le ...

As cells divide, they must copy all of their chromosomes once and only once, or chaos would ensue. How do they do it? By Amber Dance/Knowable Magazine Published Jul 7, 2023 6:00 PM EDT This article ...