Researchers have identified a specific grape compound that clashes with your metabolism, explaining why red wine causes ...

Drinking red wine can definitely cause a hangover if you consume enough of it, but for some people, enjoying even just one ...

Do you experience nausea, facial flushing or a racing heart after enjoying even small amounts of your favorite cocktail? These could be signs that you have an inherited intolerance to alcohol — and a ...

Some East Asians have a genetic mutation (ALDH2*2) that impairs the function of ALDH2. It is estimated that about 40% of Japanese people carry this mutation. The carriers of the mutation have an ...

Esophageal cancer is a global health problem. A new study found that alcohol dehydrogenase 2 (ADH2) and aldehyde dehydrogenase 2 (ALDH2) genotypes are associated with esophageal cancer risk in Chinese ...

Around 8 per cent of the world’s population has a gene variant called ALDH2*2 that impairs the body’s ability to metabolise alcohol and causes unpleasant symptoms such as flushing soon after people ...

The ALDH2 gene encodes mitochondrial aldehyde dehydrogenase 2 (ALDH2), a major acetaldehyde-metabolizing enzyme. Approximately 36% of East Asians (around 560 million people) carry an inactivating ...

Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest that healthy choices, such as increasing antioxidants and limiting ...

Our results suggest that BRCA2 p.K3326* variant, which is low-penetrance by itself, confers increased breast cancer risk on the background of the TT genotype of the ALDH2 rs10744777 variant in the ...